Spatial analysis of the AIDS mortality rate among young people in a province of the Brazilian Amazon: An ecological study

Submitted: 23 April 2022
Accepted: 9 August 2022
Published: 29 November 2022
Abstract Views: 614
PDF: 579
HTML: 13
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Worldwide, policies to combat human immunodeficiency virus (HIV) have led to a small decrease in the acquired immunodeficiency syndrome (AIDS) mortality rate among young people. For greater policy efficacy, it is necessary to determine the influence of social determinants of health (SDHs) in each territory. The objective of this study was to spatially analyse the AIDS mortality rate among young people in a province of the Brazilian Amazon and the spatial variability of the rate promoted by SDHs. All reports of AIDS deaths between 2007 and 2018 among young people living in the state of Pará were included in the study. The mortality rate was analysed using spatial distribution and autocorrelation, spatial scanning, and geographically weighted regression (GWR). During the study period, there were 1,372 deaths from AIDS among young people with a territorial expansion. The spatial autocorrelation showed two high-high clusters in the period from 2007 to 2010, one formed by municipalities in south-eastern Pará and one in the metropolitan region of Belém, with only the latter remaining between 2011 and 2018. This region showed a higher spatial risk for AIDS mortality and was the only cluster with spatiotemporal risk in the 2013-2018 period. Spatial variability was promoted by the i) the youth homicide rate, ii) the elementary school dropout rate and iii) the number of families registered in the Unified Registry for Social Programs (CadÚnico). This study provides support for the implementation of effective focal policies to combat HIV and reduce the mortality rate among young people in Pará.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Agostini R, Rocha F, Melo E, Maksud I, 2019. The Brazilian response to the HIV/AIDS epidemic amidst the crisis. Cien Saude Colet 24:4599-4604. DOI: https://doi.org/10.1590/1413-812320182412.25542019
Anselin L, 1995. Local indicators of spatial association - LISA. Geogr Anal 27:93-115. DOI: https://doi.org/10.1111/j.1538-4632.1995.tb00338.x
Barak T, Neo DT, Tapela N, Mophuthegi P, Zash R, Kalenga K, Perry ME, Malane M, Makhema J, Lockman S, Shapiro R, 2019. HIV-associated morbidity and mortality in a high ART coverage setting: prospective surveillance results from a district hospital in Botswana. J Int AIDS Soc 22:e25428. DOI: https://doi.org/10.1002/jia2.25428
Barcellos C, Feitosa P, Damacena GN, Andreazzi MA, 2010. Highways and outposts: economic development and health threats in the central Brazilian Amazon region. Int J Health Geogr 9:30. DOI: https://doi.org/10.1186/1476-072X-9-30
Box GEP, Cox DR, 1964. An analysis of transformations. J Roy Soc 26: 211-252. DOI: https://doi.org/10.1111/j.2517-6161.1964.tb00553.x
Câmara G, Carvalho MS, Cruz OG, Correa V, 2004. Análise espacial de áreas. Análise espacial de dados geográficos. Available from: http://www.dpi.inpe.br/gilberto/tutoriais/analise/cap2.pdf.
Cluver L, Meinck F, Toska E, Orkin F M, Hodes R, Sherr L, 2018. Multitype violence exposures and adolescent antiretroviral nonadherence in South Africa. AIDS 32:975-983. DOI: https://doi.org/10.1097/QAD.0000000000001795
De Sá PA, Souza SL, Ferreira GRON, Feijão AR, da Silva RAR, Gir E, Reis RK, Pereira FMV, Gonçalves LHT, Polaro SHI, Cruz AMP, Botelho EP, 2021. HIV epidemic in a province of the Brazilian Amazon region:Temporal trend analysis. J Public Health Res 11:2513. DOI: https://doi.org/10.4081/jphr.2021.2513
Do Carmo RA, Policena GM, Alencar GP, França EB, Bierrenbach AL, 2021. Underreporting of AIDS deaths in Brazil: linkage of hospital records with death certificate data. Cien Saude colet. doi:10.1590/1413-81232021264.15922019. DOI: https://doi.org/10.1590/1413-81232021264.15922019
Garnelo L, Lima JG, Rocha ESC, Herkrath FJ, 2018. Access and coverage of Primary Health Care for rural and urban populations in the northern region of Brazil. Saúde Debate 42:81-99. DOI: https://doi.org/10.1590/0103-11042018s106
IBGE, 2022. Cidades e Estados Pará. Instituto Brasileiro de Geografia e Estatística.Available from: https://www.ibge.gov.br/cidades-e-estados/pa/.html.
Kanamori M, Shrader CH, Stoler J, de Santana SA, Williams M, 2021. Geographic accessibility of HIV preventive services for young Latino men in Miami, Florida: A Cross-Sectional Study. J Assoc Nurses AIDS Care 32:68–78. DOI: https://doi.org/10.1097/JNC.0000000000000210
Lima MS, Raniere JC, Paes CJO, Gonçalves LHT, Cunha CLF, Ferreira GRON, Botelho EP, 2020. The association between knowledge about HIV and risk factors in young Amazon people. Rev Bras Enferm 73:e20190453. DOI: https://doi.org/10.1590/0034-7167-2019-0453
Maranhão TA, Alencar CH, Magalhães MAFM, Sousa JJB, Ribeiro LM, de Abreu WC, Pereira MLD, 2020. Mortality due to acquired immunodeficiency syndrome and associated social factors: a spatial analysis. Rev Bras Enferm 73:e20200002. DOI: https://doi.org/10.1590/0034-7167-2020-0002
Mee, P, 2014. Evidence for localised HIV related micro– epidemics associated with the decentralised provision of antiretroviral treatment in rural South Africa: a spatio–temporal analysis of changing mortality patterns (2007–2010). J Glob Health 4:010403. DOI: https://doi.org/10.7189/jogh.04.010403
Ministry of Health, 2018. Manual Técnico para o Diagnóstico da Infecção Pelo HIV. Departamento de DST, Aids e Hepatites Virais. Available from: http://www.aids.gov.br/pt-br/node/57787.
Ministry of Health, 2021a. BoletimEpidemiológico: HIV/Aids. Secretaria de Vigilância em Saúde. Available from: http://www.aids.gov.br/pt-br/pub/2021/boletim-epidemiologico-hivaids-2021 .
Ministry of Health, 2021b. Departamento de Condições Crônicas e Infecções Sexualmente Transmissíveis. Available from: http://www.aids.gov.br/pt-br.
Mirkuzie AH, Ali S, Abate E, Worku A, Misganaw A, 2021. Progress towards the 2020 fast track HIV/AIDS reduction targets across ages in Ethiopia as compared to neighboring countries using global burden of diseases 2017 data. BMC Public Health 21:285. DOI: https://doi.org/10.1186/s12889-021-10269-y
Mota TS, Donalisio MR, Silveira LVA, 2018. Spatial risk of death in patients with AIDS in Campinas, São Paulo, Brazil. Rev Bras Epidemiol 21:1-12. DOI: https://doi.org/10.1590/1980-549720180017
Nakaia, T, 2016. GWR4 User Manua: Windows application for geographically weighted regression modelling. Available from: https://sgsup.asu.edu/sites/default/files/SparcFiles/gwr4manual_409.pdf.
Namosha E, Sartorius B, Tanser F, 2013. Spatial clustering of all-cause and HIV-related mortality in a rural South African population (2000–2006). Plos One 8:e69279. DOI: https://doi.org/10.1371/journal.pone.0069279
Ojikutu BO, Bogart LM, Klein DJ, Galvan FH, Wagner GJ, 2018. neighborhood crime and sexual transmission risk behavior among black men living with HIV. J Health Care Poor Underserved 29:383-399. DOI: https://doi.org/10.1353/hpu.2018.0026
Okoli ML, Alao S, Ojukwu S, Emechebe N, Ikhuoria A, Kip KE, 2019. Predictive and spatial analysis for estimating the impact of sociodemographic factors on contraceptive use among women living with HIV/AIDS (WLWHA) in Kenya: Implications for policies and practice. BMJ open 9:e022221. DOI: https://doi.org/10.1136/bmjopen-2018-022221
Richards P, VanWey L, 2015. Where deforestation leads to urbanization: how resource extraction is leading to urban growth in the Brazilian Amazon. Ann Assoc Am Geogr 105:806-823. DOI: https://doi.org/10.1080/00045608.2015.1052337
Robert K, Maryline M, Jordan K, Lina D, Helgar M, Annrita I, Wanjiru M, Lilian O, 2020.Factors influencing access of HIV and sexual and reproductive health services among adolescent key populations in Kenya. Int J Public Health 65:425–432. DOI: https://doi.org/10.1007/s00038-020-01373-8
Ross JM, Henry NJ, Lindgren LAD, Lobo ADP, de Souza FM, Biehl MH, Ray SE, Jr Reiner RC, Stubbs RW, Wiens KE, Earl L, Kutz MJ, Bhattacharjee NV, Kyu HH, Naghavi M, Hay SI, 2018. Progress toward eliminating TB and HIV deaths in Brazil, 2001–2015: a spatial assessment. BMC Med 16:144. DOI: https://doi.org/10.1186/s12916-018-1131-6
Rouquayrol MZ, Gurgel M, 2018. Epidemiologia e saúde. Rio de Janeiro, Medbook8ed.
Sartorius B, 2013. Modelling determinants, impact, and space-time risk of age-specific mortality in rural South Africa: integrating methods to enhance policy relevance. Glob Health Action 6:19239. DOI: https://doi.org/10.3402/gha.v6i0.19239
Sartorius K, Sartorius B, 2013. A spatial model to quantify the mortality impact of service delivery in Sub-Saharan Africa: an ecological design utilizing data from South Africa. Int J Health Geogr 12:8. DOI: https://doi.org/10.1186/1476-072X-12-8
SICLOM, 2021. Sistema de Controle Logístico de Medicamentos. Available from: http://azt.aids.gov.br/.
Sifuna P, Otieno L, Andagalu B, Oyieko J, Ogutu B, Singoei V, Owuoth J, Ogwang S, Cowden J, Otieno W, 2018. A Spatiotemporal Analysis of HIV-Associated Mortality in Rural Western Kenya 2011–2015. J Acquir Immune Defic Syndr 78:1097. DOI: https://doi.org/10.1097/QAI.0000000000001710
Teixeira TRA, Gracie R, Malta MS, Bastos FI, 2014. Social geography of AIDS in Brazil: identifying patterns of regional inequalities. Cad Saude Publica 30:259-271. DOI: https://doi.org/10.1590/0102-311X00051313
Thapa S, Hannes K, Cargo M, Buve A, Peters S, Dauphin S, Mathei C, 2018. Stigma reduction in relation to HIV test uptake in low- and middle-income countries: a realist review. BMC Public Health 18:1277. DOI: https://doi.org/10.1186/s12889-018-6156-4
UNAIDS, 2021a. Unaids Data. The Joint United Nations Programme on HIV/AIDS. Available from:https://www.unaids.org/sites/default/files/media_asset/JC3032_AIDS_Data_book_2021_En.pdf
UNAIDS, 2021b. Global AIDS Updade. Young people and HIV.The Joint United Nations Programmeon HIV/AIDS. Available from: https://www.unaids.org/sites/default/files/media_asset/young-people-and-hiv_en.pdf.
Viana JN, Moyses RPC, Espir TT, de Souza GA, Barcellos JFM, Alves MGP, 2019.Social determinants of health and secondary prevention of cervical cancer in the state of Amazonas, Brazil. Medicine USP 52:110-120. DOI: https://doi.org/10.11606/issn.2176-7262.v52i2p110-120
Zhang X, Tang W, Li Y, Mahapatra T, Feng Y, Li M, Chen F, Li P, Xing J, Qian S, Ge L, Bu K, Mahapatra S, Tang S, Wang L, Wang N, 2017. The HIV/AIDS epidemic among young people in China between 2005 and 2012: results of a spatial temporal analysis. HIV Med 18:141–150. DOI: https://doi.org/10.1111/hiv.12408

How to Cite

Lago Sousa, S. M., Pedroso , . A. O. ., Seabra , I. L. . ., Oliveira Naiff Ferreira, G. R., Pereira Cruz Ramos , A. M. ., Polaro, S. H. I. ., & Pinheiro Botelho, E. (2022). Spatial analysis of the AIDS mortality rate among young people in a province of the Brazilian Amazon: An ecological study. Geospatial Health, 17(2). https://doi.org/10.4081/gh.2022.1102